Faculty
| Faculty Member | Photo | Research Description | Areas |
|---|---|---|---|
| Siddhesh Aras, MBBS, PhD |  |
Oxidative phosphorylation, Role of mitochondria in infectious diseases, Transcriptional regulation of mitochondrial proteins. | Cell and Molecular Biology Biochemistry Microbiology |
| Erin Carmany, MS, CGC 313-577-9138 ecarmany@med.wayne.edu |
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Genetic counseling in the Spanish speaking population, alternative genetic counseling service models, written patient communication. | Genetic Counseling |
| Tiffany Cook, PhD 313-577-9461 tiffany.cook.cmmg@gmail.com |
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Molecular basis of eye development and disease; differentiation and maintenance of neuronal and non-neuronal cell types in the Drosophila retina; glial support mechanisms; cell-specific transcriptional regulatory mechanisms; cell-cell interactions involved in sensory system development and function. |
Genetics Genomics Neuroscience Protein Structure & Function |
| Gerald Feldman, MD, PhD 313-577-6298 gfeldman@med.wayne.edu |
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Use of molecular technologies in the diagnosis of genetic diseases, clinical genetics, and dysmorphology; educational programs in medical genetics residency training. | Genetics Genetics Counseling Medical Genetics |
| Russell L. Finley, Jr., PhD 313-577-7845 rfinley@wayne.edu |
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Regulatory networks that control cell proliferation; cell cycle regulation during development; high throughput technologies to study protein interaction networks. | Cancer Biology Cell & Molecular Biology Developmental Biology Genetics. Proteomics |
| Samiran Ghosh, PhD 313-577-5346 sghos@med.wayne.edu |
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Survival analysis, generalized linear model, multilevel model, model selection in high dimensional data, machine learning and Bayesian paradigm. |
Biostatistics Computational Biology
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| Alexander Gow, PhD 313-577-9401 agow@med.wayne.edu |
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Role of the unfolded protein response in neurodegenerative diseases; molecular characterization of the regulation of axoglial junction assembly in CNS myelin; molecular characterization of the claudin family of integral membrane tight junction proteins during development in brain, testes, and inner ear using transgenic and homologous recombination in embryonic stem cells. | Cell & Molecular Biology Developmental Biology Genomics Medical Genetics Neurosciences Proteomics |
| James G. Granneman, PhD 313-577-5629 james.granneman@wayne.edu |
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Adipose tissue cell and molecular biology, target identification and high through-put screening for novel obesity and diabetes therapeutics. |
Cell & Molecular Biology Cell Signaling Diabetes Metabolism Protein Structure & Function |
| Lawrence I. Grossman, PhD 313-577-5326 l.grossman@wayne.edu |
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Molecular Genetics and evolution of the electron transport chain; cytochrome c oxidase; mitochondria and mitochondrial diseases. | Cell & Molecular Biology Genetics Genomics Molecular Evolution |
| Henry H.Q. Heng, PhD 313-577-9544 hheng@med.wayne.edu |
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Molecular cytogenetics; genome structure and function; genomic instability and cancer progression. | Cancer Biology Chromatin Structure & Function Genomics |
| Maik Hüttemann, PhD 313-577-9150 mhuttema@wayne.edu |
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Function of cytochrome c oxidase isoforms, oxygen sensing, and role of mitochondria in cancer. | Cancer Biology Cell & Molecular Biology Developmental Biology Genetics Medical genetics Neurosciences Proteomics |
| Stephen A. Krawetz, PhD 313-577-6770 steve@compbio.med.wayne.edu |
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Gene Therapy; control of development and differentiation; expression of connective tissue genes and genes controlling spermatogenesis; computer-assisted sequence analysis. | Bioinformatics Cell & Molecular Biology Chromatin Structure & Function Developmental Biology Gene Therapy Genetics Genomics Medical Genetics |
| Susan J. Land, PhD 313-577-9605 sland@med.wayne.edu |
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Genomics | Cancer Biology Genetics Medical Genetics Neurosciences |
| Li Li, PhD 313-577-8749 lili@med.wayne.edu |
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Gene regulation during cardiovascular and hematopoietic development. | Cell & Molecular Biology Developmental Biology |
| Leonard Lipovich, PhD 313-577-9683 llipovich@med.wayne.edu |
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Genomic complexity; bioinformatics and functional genomics of long noncoding-RNA transcripts; primate-specific genes; computing the genomic basis of species phenotypic uniqueness. | Bioinformatics Genetics Genomics |
| Francesca Luca, PhD 313-577-1152 fluca@wayne.edu |
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Functional and population genomics of intermediate phenotypes. Gene-environment interactions. | Functional Genomics Population Genetics Bioinformatics Genetics |
| Roger Pique-Regi, PhD 313-577-0719 rpique@wayne.edu |
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Computational methods and statistical genetic models to study regulation of gene transcription, chromatin state/accessibility, gene-environment interactions, and genetics of complex traits. Machine learning and integrative hierarchical Bayesian analysis of large genomic datasets (RNA-seq, ChIP-seq, DNA methylation, DNase-seq, ATAC-seq and also their single cell resolution variants) with genetic variation associated with molecular (eQTL) and complex traits (GWAS). |
Bioinformatics Statistical Genetics Functional and Computational Genomics Single Cell Genomics Gene Regulation Regulation of Chromatin State |
| Lobelia Samavati, MD 313-745-1718 lobi@wayne.edu |
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Clinical and laboratory research in sarcoidosis and interstitial lung disease. | Molecular Medicine Genetics |
| Shengyi Iris Sun, PhD 313-577-0646 shengyisun@wayne.edu |
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The role of ER-associated degradation and inflammation in health and disease. |
Metabolism Diabetes Protein Structure and Function |
|
Michael A. Tainsky, PhD
|
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Cancer genetic studies of familial cancers to determine the inherited cancer genes, analyze the mechanism of their action, and factors affecting genetic penetrance of the cancer phenotype. | Bioinformatics Cancer Biology Cell & Molecualr Biology Genetic Counseling Genetics Genomics Proteomics |
| Angela M. Trepanier, MS, CGC 313-577-3425 atrepani@med.wayne.edu |
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Educational programs in human genetics and genetic counseling; cancer genetics. | Genetic Counseling Medical Genetics |
| Jeffrey Tseng, PhD 313-577-0498 ytseng@wayne.edu |
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Protein structure, function, classification and evolution; Disease-associated non-synonymous single-nucleotide polymorphism; Geometric matching techniques; Geometric modeling and molecular simulation. | Computational Structural Biology Molecular Structural Evolution Bioinformatics |
| Kezhong Zhang, PhD 313-577-2669 kzhang@med.wayne.edu |
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Intracellular stress signaling from the endoplasmic reticulum and mitochondria; unfolded protein response and inflammation in metabolic diseases. | Cell and Molecular Biology Developmental Biology Genetics Immunology Signal Transduction |
| Ren Zhang, PhD 313-577-0027 rzhang@med.wayne.edu |
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Obesity and diabetes; the leptin signaling pathway and mechanisms of leptin resistance; comparative genomics. |
Molecular Genetics Metabolism Cell Signaling |
Emeritus Faculty
| Faculty Member | Photo | Research Description | Areas |
|---|---|---|---|
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Cellular and molecular biology of monoamine neurotransmitter secreting neurons. | Neurosciences | |
| Wayne D. Lancaster, PhD lancaster@wayne.edu |
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Papillomaviruses: molecular biology, evolution, and role in human carcinogenesis; cancer cell genome instability; ovarian carcinogenesis. | Cancer Biology Cell&Molecular Biology Medical Genetics |
Secondary Faculty
| Faculty Member | Photo | Research Description | Areas |
|---|---|---|---|
| Kang Chen, PhD 313-578-4339 kang@wayne.edu |
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Mucosal Immunology, Reproductive immunology, Immunodeficiency, infection and inflammation, Cancer Immunology. | |
| Felix Fernandez-Madrid, MD, PhD 313-577-1133 aa1108@wayne.edu |
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Rheumatoid Arthritis and Autoimmune Diseases. | |
| Zhengqing Hu, MD, PhD 313-577-0594 zh@med.wayne.edu |
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Cell Culture, Cell Biology, Molecular Biology, Immunocytochemistry, Advanced Microscopy, Inner Ear Transplantation, and Functional Evaluation of Hearing. | |
| Bhanu Jena, PhD 313-577-1532 bjena@med.wayne.edu |
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Cellular and Molecular Processes Involved in Protein Secretion and Exocytosis. |
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| Jun Li, MD, PhD 313-577-1245 junli@med.wayne.edu |
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Inherited Peripheral Nerve Diseases, Myelin Biology, Motor Neuron Diseases, Electromyography, Skin Biopsy for Evaluation of Peripheral Nerve Diseases. | |
| Karin Przyklenk, PhD 313-577-4630 kprzykle@med.wayne.edu |
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Conducting translational, bench-to-bedside research focusing on the pathophysiology of acute coronary ischemic syndromes, the identification of cellular mechanisms and signaling pathways that increase the tolerance of the myocardium to ischemia, and the development of novel strategies to limit damage caused to the heart by ischemia-reperfusion. | |
| Douglas Ruden, PhD 313-577-6688 douglasr@wayne.edu |
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Toxicogenomics of heavy metal exposure using Drosophila and human embryonic stem cell models. | |
| Marianna Sadagurski, PhD 313-577-8637 sadagurski@wayne.edu |
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Obesity and Diabetes, Nutrient-sensing hypothalamic circuits, Neurobiology of aging, Early postnatal environment. | |
| Assia Shisheva, PhD 313-577-5674 ashishev@med.wayne.edu |
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Cellular and molecular physiology: Role for phosphoinositides in controlling membrane trafficking and peptide hormone signaling. | |
| Robert Skoff, PhD 313-577-1165 rskoff@med.wayne.edu |
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Studies the role of proteolipid protein in neonatal hypoxia ischemia and research of proteins in the myelin sheath that are critical for normal human function. | |
| Jiemei Wang, MD, PhD 313-577-1715 jiemei.wang@wayne.edu |
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Diabetes, Cardiovascular disorders, Angiogenesis, Endothelium, Stress signaling. |
NBSI Progress Report 2019