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Graduate Programs in Molecular Genetics and Genomics

Challenging, research intensive PhD and MS graduate programs which prepare students for careers in academia and industry.

Genetics Residencies & Fellowships

Provide medical care to patients with birth defects, metabolic diseases, and a family history of inherited conditions.

MASTERS DEGREE IN GENETIC COUNSELING

Develop the skills and knowledge to become a professional genetic counselor.

AGRADE PROGRAM

Get a jump on graduate study with this novel Accelerated Graduate Enrollment program.

news

CMMG faculty, Dr. James Granneman, leading the new Barber Integrative Metabolic Research Program. Alongside a multidisciplinary team of researchers, Dr. Granneman will be investigating the "understanding the intricacies of cellular lipid metabolism" in an effort to understand the progression of many metabolic diseases. Read more about this new initiative here!

Research by CMMG faculty, Dr. Kezhong Zhang, was recently selected and featured by Medicine Innovates. Read about his featured researchDiscovery of CREBH-C: A Novel Hepatokine Regulating Lipoprotein Lipase Activity and Metabolic Disorders

Dr. Cristina Espinosa-Diez has joined CMMG faculty as an Assistant Professor: Joint with the Physiology department, Dr. Espinosa-Diez joined our faculty on October 1st, welcome!

Dr. Russell Finley was awarded the 2023 SOM College Teaching Award.

Dr. Roger Pique Regi was awarded the 2023 SOM Research Excellence Award.

Dr. Siddhesh Aras, serves as a scientist reviewer on the 2023 Department of Defense Directed Medical Research Program.

Dr. Li Li's recent publication in the Vascular Pharmacology journal, has been chosen as the Editor's Choice Article for September. Insights into elastic fiber fragmentation: Mechanisms and treatment of aortic aneurysm in Marfan syndrome.

Former CMMG Ph.D. student (now faculty at University of Wisconsin), Dr. Ze Zheng, has published an article in Science Magazine: Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes.

Upcoming Events

For more information email Suzanne Shaw 

Jan
11

11:00 a.m., 2268 Scott Hall

MGG Student/PostDoc Seminar Series: Shreya Nirmalan

Calendar of Events

 

CMMG Spotlight:

Newsletter articles highlighting CMMG faculty, students, and events. Click here to read other articles from the CMMG newsletter.

CREBH-C, a new hepatokine that helps control triglyceride levels 

Featuring the recent work of Dr. Kezhong Zhang, Ph.D., regarding CREBH-C and its implications

 

 

Focus on CMMG graduate students: Paul Morse

Featuring former M.D.-Ph.D. student, Paul Morse, who worked with Dr. Maik Hüttemann

 

 

Ischemia Reperfusion Injury: from the lab to the clinic

Featuring the work of Dr. Maik Hüttemann, Ph.D., who was recently awarded a NIH U44 grant for this work.

 

 

Racial disparities in cancer genetic counseling being examined 

Featuring Erin Carmany, M.S., CGC, Associate Professor of Molecular Medicine and Genetics Associate Director, Genetic Counseling Masters Program

New collaboration to evaluate large-scale proteomics data for prediction of preeclampsia

Dr. Adi Tarca, Ph.D., has established a collaboration with Dr. Trond Michelson, University of Oslo (Norway), to conduct a cross-cohort evaluation of large-scale proteomics data for the prediction of preeclampsia. A postdoctoral researcher from Dr. Michelson's lab will join Dr. Tarca's lab at CMMG for 6 months to work on this collaborative project.

Recent research 

Insights into elastic fiber fragmentation: Mechanisms and treatment of aortic aneurysm in Marfan syndrome. Seeburun S, Wu S, Hemani D, Pham L, Ju D, Xie Y, Kata P, Li L. Vascul Pharmacol. 2023 Aug 26;153:107215. doi: 10.1016/j.vph.2023.107215. Epub ahead of print. PMID: 37640090.

Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells. Kaur H, Minchella P, Alvarez-Carbonell D, Purandare N, Nagampalli VK, Blankenberg D, Hulgan T, Gerschenson M, Karn J, Aras S, Kallianpur AR.  Int J Mol Sci. 2023 Jul 31;24(15):12242. doi: 10.3390/ijms241512242. PMID: 37569616; PMCID: PMC10419149

The MNRR1 activator nitazoxanide abrogates lipopolysaccharide-induced preterm birth in mice. Purandare N, Gomez-Lopez N, Arenas-Hernandez M, Galaz J, Romero R, Xi Y, Fribley AM, Grossman LI, Aras S. Placenta. 2023 Jul 8;140:66-71. doi: 10.1016/j.placenta.2023.07.005. Epub ahead of print. PMID: 37544161.

Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution. Resztak JA, Wei J, Zilioli S, Sendler E, Alazizi A, Mair-Meijers HE, Wu P, Wen X, Slatcher RB, Zhou X, Luca F, Pique-Regi R. Genome Res. 2023 Jun; 33(6):839-856. doi: 10.1101/gr.276765.122.

Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle. Morse PT, Pérez-Mejías G, Wan J, Turner AA, Márquez I, Kalpage HA, Vaishnav A, Zurek MP, Huettemann PP, Kim K, Arroum T, De la Rosa MA, Chowdhury DD, Lee I, Brunzelle JS, Sanderson TH, Malek MH, Meierhofer D, Edwards BFP, Díaz-Moreno I, Hüttemann M. Nat Commun. 2023 Jul 13;14(1):4166. doi: 10.1038/s41467-023-39820-8.

The New Year of Systems Biology in Reproductive Medicine. Krawetz SA. 2023. Sys Biol Reprod Med.13:1-2. doi: 10.1080/19396368.2023.2156032. 

Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin. Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D, Huang YM, Zhang K, Shah YM, Sun S. 2023. Proc Natl Acad Sci USA. doi:10.1073/pnas.2212644120 

Mitochondrial NAD kinase in health and disease. Zhang R, Zhang K. Redox Biol. 2023 Apr; 60:102613. doi: 10.1016/j.redox.2023.

BCL2 is a major regulator of haploidy maintenance in murine embryonic stem cells. Sun S, Zhao Q, Zhao Y, Geng M, Wang Q, Gao Q, Zhang XO, Zhang W, Shuai L. Cell Prolif. 2023 May 5:e13498. doi: 10.1111/cpr.13498. Epub ahead of print. PMID: 37144356. 

Challenges and Opportunities for Clinical Cytogenetics in the 21st Century. Heng E, Thanedar S, Heng HH. 2023 Feb 15;14(2):493. doi: 10.3390/genes14020493. PMID: 36833419; PMCID: PMC9956237.