Lobelia Samavati, MD

Lobelia Samavati, MD
Associate Professor of Molecular Medicine and Genetics and of Internal Medicine
Director, Sarcoidosis/ILD Center
Scott Hall, Rm 3228
540 E. Canfield Avenue
Detroit, MI 48201
313-745-1718
lobi@wayne.edu

Education

Medical School at the University of Cologne, MD, 1992

Research Focus

Clinical and laboratory research in sarcoidosis and interstitial lung disease

Recent Publications

Rastogi R, Jiang Z, Ahmad N, Rosati R, Liu Y, Beuret L, Monks R, Charron J, Birnbaum MJ, Samavati L. Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways. J Biol Chem. 2013 Nov 22;288(47):33966-77. doi: 10.1074/jbc.M113.492702. Epub 2013 Oct 14. PubMed PMID: 24126911; PubMed Central PMCID: PMC3837136.

Krell W, Bourbonnais JM, Kapoor R, Samavati L. Effect of smoking and gender on pulmonary function and clinical features in sarcoidosis. Lung. 2012 Oct;190(5):529-36. Epub 2012 Jul 8. PubMed PMID: 22773249.

Bourbonnais JM, Malaisamy S, Dalal BD, Samarakoon PC, Parikh SR, Samavati L. Distance saturation product predicts health-related quality of life among sarcoidosis patients. Health Qual Life Outcomes. 2012 Jun 13;10:67. doi: 10.1186/1477-7525-10-67. PubMed PMID: 22694853; PubMed Central PMCID: PMC3409072.

Hüttemann M, Helling S, Sanderson TH, Sinkler C, Samavati L, Mahapatra G, Varughese A, Lu G, Liu J, Ramzan R, Vogt S, Grossman LI, Doan JW, Marcus K, Lee Regulation of mitochondrial respiration and apoptosis through cell signaling: cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation. Biochim Biophys Acta. 2012 Apr;1817(4):598-609. doi: 10.1016/j.bbabio.2011.07.001. Epub 2011 Jul 13. Review. PubMed PMID: 21771582; PubMed Central PMCID: PMC3229836.

Bauerfeld CP, Rastogi R, Pirockinaite G, Lee I, Hüttemann M, Monks B, Birnbaum MJ, Franchi L, Nuñez G, Samavati L. TLR4-mediated AKT activation is MyD88/TRIF dependent and critical for induction of oxidative phosphorylation and mitochondrial transcription factor A in murine macrophages. J Immunol. 2012 Mar 15;188(6):2847-57. doi: 10.4049/jimmunol.1102157. Epub 2012 Feb 6. PubMed PMID: 22312125; PubMed Central PMCID: PMC3294201.

Cumbo-Nacheli G, Samavati L, Guzman JA. Bioavailability of fondaparinux to critically ill patients. J Crit Care. 2011 Aug;26(4):342-6. doi: 10.1016/j.jcrc.2010.08.004. Epub 2010 Oct 2. PubMed PMID: 20889286.