Siddhesh Aras works on oxidative phosphorylation, role of mitochondria in infectious diseases, transcriptional regulation of mitochondrial proteins.
Erin Carmany is a genetic counselor who works on genetic counseling in the Spanish speaking population, alternative genetic counseling service delivery models, patient written communication.
Tiffany Cook works on molecular basis of eye development and disease; differentiation and maintenance of neuronal and non-neuronal cell types in the Drosophila retina; glial support mechanisms; cell-specific transcriptional regulatory mechanisms
Gerald Feldman works on use of molecular technologies in the diagnosis of genetic diseases, clinical genetics, and dysmorphology; educational programs in medical genetics residency training, newborn screening and inborn errors of metabolism.
Russell Finley’s research follows two main themes. One is understanding how regulatory networks control biological processes. Our approach is to identify and characterize networks of interacting genes and proteins using high throughput technologies, A second theme is directed at understanding the molecular mechanisms that control cell division.
Samiran Ghosh is a statistician whose methodological research focuses on survival analysis, generalized linear model, multilevel model, model selection in high dimensional data, machine learning and Bayesian paradigm. He is also interested in design and analysis of clinical trials. On the application side his major focus is on health services, outcomes research and mental health.
Alexander Gow works on the unfolded protein response in neurodegenerative diseases; molecular characterization and regulation of axoglial junction assembly in CNS myelin; molecular characterization of the claudin family of integral membrane tight junction proteins during development; learning and memory deficits in neurodegenerative disease.
James Granneman works on adipose tissue cell and molecular biology; therapeutic adipose tissue remodeling; single cell functional genomics; molecular biology and biophysics of lipolysis activation; co-evolution of lipid droplet binding proteins; molecular pharmacology of ABHD5, a novel therapeutic target for metabolic disease and cancer.
Molecular Genetics and evolution of the electron transport chain; cytochrome c oxidase; mitochondria and mitochondrial diseases.
Molecular cytogenetics; genome structure and function; genomic instability and cancer progression.
Function of cytochrome c oxidase isoforms, oxygen sensing, and role of mitochondria in cancer.
Gene Therapy; control of development and differentiation; expression of connective tissue genes and genes controlling spermatogenesis; computer-assisted sequence analysis.
Genomics Cancer Biology Genetics.
Gene regulation during cardiovascular and hematopoietic development. Cell & Molecular Biology
Functional and population genomics of intermediate phenotypes. Gene-environment interactions. Functional Genomics
Computational methods and statistical genetic models to study regulation of gene transcription, chromatin state/accessibility, gene-environment interactions, and genetics of complex traits. Machine learning and integrative hierarchical Bayesian analysis of large genomic datasets (RNA-seq, ChIP-seq, DNA methylation, DNase-seq, ATAC-seq and also their single cell resolution variants) with genetic variation associated with molecular (eQTL) and complex traits (GWAS).
Clinical and laboratory research in sarcoidosis and interstitial lung disease. Molecular Medicine.
The role of ER-associated degradation and inflammation in health and disease.
Cancer genetic studies of familial cancers to determine the inherited cancer genes, analyze the mechanism of their action, and factors affecting genetic penetrance of the cancer phenotype. Bioinformatics.
Developing and evaluating educational approaches for integrating genomics into primary care; evaluating ways to increase access to genetic counseling services; investigating genetic counseling outcomes; genetic counseling student education, recruitment, and evaluation; genetic counselor career advancement.
Protein structure, function, classification and evolution; Disease-associated non-synonymous single-nucleotide polymorphism; Geometric matching techniques; Geometric modeling and molecular simulation. Computational Structural Biology.
Intracellular stress signaling from the endoplasmic reticulum and mitochondria; unfolded protein response and inflammation in metabolic diseases. Cell and Molecular Biology.
Obesity and diabetes; the leptin signaling pathway and mechanisms of leptin resistance; comparative genomics.
|Faculty Member||Photo||Research Description||Areas|
|Cellular and molecular biology of monoamine neurotransmitter secreting neurons.||Neurosciences|
|Wayne D. Lancaster, PhD
|Papillomaviruses: molecular biology, evolution, and role in human carcinogenesis; cancer cell genome instability; ovarian carcinogenesis.||Cancer Biology
|Faculty Member||Photo||Research Description||Areas|
|Kang Chen, PhD
|Mucosal Immunology, Reproductive immunology, Immunodeficiency, infection and inflammation, Cancer Immunology.|
|Felix Fernandez-Madrid, MD, PhD
|Rheumatoid Arthritis and Autoimmune Diseases.|
|Zhengqing Hu, MD, PhD
|Cell Culture, Cell Biology, Molecular Biology, Immunocytochemistry, Advanced Microscopy, Inner Ear Transplantation, and Functional Evaluation of Hearing.|
|Bhanu Jena, PhD
Cellular and Molecular Processes Involved in Protein Secretion and Exocytosis.
|Jun Li, MD, PhD
|Inherited Peripheral Nerve Diseases, Myelin Biology, Motor Neuron Diseases, Electromyography, Skin Biopsy for Evaluation of Peripheral Nerve Diseases.|
|Karin Przyklenk, PhD
|Conducting translational, bench-to-bedside research focusing on the pathophysiology of acute coronary ischemic syndromes, the identification of cellular mechanisms and signaling pathways that increase the tolerance of the myocardium to ischemia, and the development of novel strategies to limit damage caused to the heart by ischemia-reperfusion.|
|Douglas Ruden, PhD
|Toxicogenomics of heavy metal exposure using Drosophila and human embryonic stem cell models.|
|Marianna Sadagurski, PhD
|Obesity and Diabetes, Nutrient-sensing hypothalamic circuits, Neurobiology of aging, Early postnatal environment.|
|Assia Shisheva, PhD
|Cellular and molecular physiology: Role for phosphoinositides in controlling membrane trafficking and peptide hormone signaling.|
|Robert Skoff, PhD
|Studies the role of proteolipid protein in neonatal hypoxia ischemia and research of proteins in the myelin sheath that are critical for normal human function.|
|Jiemei Wang, MD, PhD
|Diabetes, Cardiovascular disorders, Angiogenesis, Endothelium, Stress signaling.|