2024
Mitochondrial Oxidative Phosphorylation in Viral Infections. Purandare N, Ghosalkar E, Grossman LI, Aras S (2024). Viruses, 15(12):2380. doi: 10.3390/v15122380.
Resonance Raman spectral analysis on the heme site structure of cytochrome c oxidase with its positive regulator CHCHD2. Yanagisawa S, Kamei T, Shimada A, Gladyck S, Aras S, Hüttemann M, Grossman LI, Kubo M (2024). J Inorganic Biochem, 2024 Nov;260:112673. doi: 10.1016/j.jinorgbio.2024.112673. Epub 2024 Jul 25. PMID: 39094247.
To boldly go where no microRNAs have gone before: Spaceflight impact on risk for small-for-gestational-age infants. Corti1 G, Kim J, Enguita FJ, Guarnieri JW, Grossman LI, Costes SV, Fuentealba M, Scott RT, Magrini A, Sanders LM, Singh K, Sen CK, Juran CM, Paul AM, Furman D, Calleja-Agius J, Mason CE, Galeano D, Bottini M, Beheshti A (2024). Communications Biology, Oct 5;7(1):1268. doi: 10.1038/s42003-024-06944-6.PMID: 39369042.
Inborn Metabolic Defects of Mitochondria. Aras S and Grossman, LI (2024). In Brady et al., editors, “Basic Neurochemistry” (Elsevier). In press.
2023
Non-coding regions of nuclear-DNA-encoded mitochondrial genes and lncRNAs are targeted by autoantibodies in breast cancer. Obaidat D, Giordo R, Kleinbrink EL, Banisad E, Grossman LI, Arshad R, Stark A, Maroun MC, Lipovich L, Fernández Madrid F (2023). Frontiers Genet, DOI 10.3389/fgene.2022.970619.
MNRR1 is a driver of ovarian cancer progression. Chehade H, Purandare N, Fox A, Adzibolosu N, Jayee S, Singh A, Tedja R, Gogoi R, Aras S, Grossman LI, Mor G, Alvero AB (2023). Translational Oncology, Mar;29:101623. doi: 10.1016/j.tranon.2023.101623.
Evidence for the participation of CHCHD2/MNRR1, a mitochondrial protein, in spontaneous labor at term and in preterm labor with intra-amniotic infection. Bosco M, Romero R, Gallo D, Suksai M, Gotsch F, Jung E, Chaemsaithong P, Tarca AL, Gomez-Lopez N, Arenas-Hernandez M, Meyyazhagan A, Al Gasem M, Grossman LI, Aras S, Chaiworapongsa T (2023). J Maternal- Fetal & Neonatal Medicine, Dec;36(1):2183088. doi: 10.1080/14767058.2023.2183088. PMID: 36941246.
Clinical chorioamnionitis at term is characterized by changes in the plasma concentration of CHCHD2/MNRR1, a mitochondrial protein. Bosco M, Romero R, Gallo D, Suksai M, Gotsch F, Jung E, Chaemsaithong P, Tarca AL, Gomez-Lopez N, Arenas-Hernandez M, Meyyazhagan A, Al Gasem M, Franchi, MP, Grossman LI, Aras S, Chaiworapongsa T (2023). J Maternal-Fetal & Neonatal Medicine, Dec;36(2):2222333. doi: 10.1080/14767058.2023.2222333. PMID: 37349086.
The MNRR1 activator nitazoxanide abrogates lipopolysaccharide- induced preterm birth in mice. Purandare N, Gomex-Lopez N, Arenas-Hernandez M, Galaz J, Romero R, Xi Y, Fribley AM, Grossman LI, Aras S (2023). Placenta 140, 66–71.
A mitochondrial regulator protein, MNRR1, is elevated in the maternal blood of women with preeclampsia. Suksai M, Romero R, Bosco M, Gotsch F, Jung E, Chaemsaithong P, Tarca AL, Gudicha, DW, Gomez-Lopez N, Arenas-Hernandez M, Meyyazhagan A, Grossman LI, Aras S, Chaiworapongsa T (2023). J Maternal-Fetal & Neonatal Medicine, doi.org/10.1080/14767058.2023.2297158
2022
Lipopolysaccharide induces placental mitochondrial dysfunction by reducing MNRR1 levels via a TLR4-independent pathway. Purandare N, Kunji Y, Xi Y, Romero R, Gomez-Lopez N, Fribley A, Grossman LI, Aras S (2022). iScience, Oct 12;25(11):105342. doi: 10.1016/j.isci.2022.105342.
An explanation for the decreased severity of liver malfunction in Niemann-Pick C1 disease with age. Erickson RP, Grossman LI, and Aras S (2022). J Applied Genetics, doi: 10.1007/s13353-022- 00695-y. PMID: 35508755
Fetal and Maternal NLRP3 Signaling is Required for Preterm Labor and Birth. Motomura K, Romero R, Galaz J, Tao L, Garcia-Flores V, Xu Y, Done B, Arenas-Hernandez M, Miller D, Gutierrez-Contreras P, Farias-Jofre M, Aras S, Grossman LI, Tarca AL, Gomez-Lopez N (2022). JCI Insight, 2022;7(16):e158238. https://doi.org/10.1172/jci. insight.158238.
Mitochondrial oxygen sensing of acute hypoxia in specialized cells - is there a unifying mechanism? Pak O, Nolte A, Knoepp F, Giordano L, Pecina P, Hüttemann M, Grossman LI, Weissmann N, Sommer N (2022). Biochim Biophys Acta Bioenerg, DOI: 0.1016/j.bbabio.2022.148911 PMID:Curriculum vitae Page 1535988811.
2021
Mitochondrial metabolism and carcinogenesis. Aras S, Purandare N, Grossman LI (2021). In “Mitochondrial Metabolism,” Editors Jalal Pourahmad and Mohsen Rezaei, Elsevier: Academic Press, pp 119-154. ISBN 978-0-12-822416-8.
Mitochondrial respiration is controlled by allostery, subunit composition and phosphorylation sites of cytochrome c oxidase: A trailblazer’s tale – Bernhard Kadenbach. Vogt S, Ramzan R, Grossman LI, Singh KK, Ferguson-Miller S, Yoshikawa S, Lee I, Hüttemann M. Mitochondrion 60: 228-233.
Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy. Purandare N, Minchella P, Somayajulu M, Kramer K, Zhou J, Adekoya N, Welch RA, Grossman LI, Aras S, Recanati M-A. Placenta 106: 40-48.
Regulation of COX Assembly and Function by Twin CX9C Proteins – Implications for Human Disease. Gladyck S, Aras S, Hüttemann M, Grossman LI. Cells Jan 20;10(2):197. doi: 10.3390/cells10020197.
2020
Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1nmf164. Erickson RP, Aras S, Hüttemann M, Dragotto J, Fiorenza MT, and Grossman LI (2020). Mitochondrion, 51:15-21. doi: 10.1016/j.mito.2019.12.003. PMID: 31862414.
Acute oxygen sensing through HIF2a-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors. Moreno-Domínguez A, Ortega-Sáenz P, Gao L, Colinas O, García-Flores P, Bonilla-Henao V, Aragonés J, Hüttemann M, Grossman LI, Weissmann N, Sommer N, López-Barneo J (2020). Science Signaling, 13(615). pii: eaay9452. doi: 10.1126/scisignal.aay9452. PMID: 31848220.
Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis. Kalpage HA, Wan J, Morse PT, Zurek MP, Turner AA, Khobeir A, Yazdi N, Hakim A, Liu J, Vaishnav A, Sanderson TH, Recanati M-A, Grossman LI, Lee I, Edwards BFP, Hüttemann M (2020). Int J Biochem Cell Biol, 121:105704. doi: 10.1016/j.biocel.2020.105704. PMID: 32023432.
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype in MELAS by inducing stress responsive homeostatic mechanisms. Aras S, Purandare N, Glayck S, Somayajulu-Nitu M, Zhang K, Wallace DC, Grossman LI (2020). Proc Natl Acad Sci USA, in press. PMID: 33257573
Intraperitoneal Triamcinolone May Reduce Adhesion Formation After Abdominal Myomectomy Through Alteration of Mitochondrial Function. Purandare N, Kramer K, Minchella P, Walker C, Hüttemann M, Grossman LI, Berman J, Aras S, and Recanati M-A (2020). Fertility and Sterility, in press.
Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review. 169. Madrid FF, Grossman LI, Aras S (2020). J Cancer Immunol 2(4): 138-158.
2019
HIF-1α Regulates IL-1β and IL-17 in Sarcoidosis. Talreja J, Talwar H, Bauerfeld C, Tranchida P, Grossman LI, and Samavati L (2019). eLife, May 1;8. pii: e44519. doi: 10.7554/eLife.44519.
Mitochondrial autoimmunity and the role of MNRR1 in breast carcinogenesis. Aras S, Maroun MC, Song Y, Bandyopadhyay S, Stark A, Yang Z, Grossman LI, and Fernández-Madrid F (2019). BMC Cancer. 19: 411. doi: 10.1186/s12885-019-5575-7.
Serine-47 Phosphorylation of Cytochrome c in the Mammalian Brain Regulates Mitochondrial Respiration and Apoptosis. Kalpage H, Vaishnav A, Liu J, Varughese A, Wan J, Ji Q, Kapralov AA, Kagan VE, Brunzelle JS, Recanati MA, Grossman LI, Sanderson TH, Lee I, Salomon RE, Edwards BFP, Hüttemann M (2019. FASEB J, 33(12):13503-13514. doi: 10.1096/fj.201901120R. PMID: 31570002.
Cytochrome c Threonine 58 phosphorylation Regulates Respiration and Apoptosis. Wan J, Kalpage H, Vaishnav A, Liu J, Lee I, Mahapatra G, Moraes CT, Recanati M-A, Grossman LI, Salomon AR, Edwards BFP, Hüttemann M (2019). Scientific Reports, 9(1):15815. doi: 10.1038/s41598-019-52101-z. PMID: 31676852.
Letter by Hüttemann et al Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction." Hüttemann M, Sommer N, Weissmann N, Grossman LI (2019). Circ Res 125(8): e33-e34. doi: 10.1161/CIRCRESAHA.119.315815.
2018
Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury. Sanderson TH, Wider JM, Lee I, Reynolds CA, Liu J, Lepore B, Tousignant R, Bukowski MJ, Johnston H, Fite A, Raghunayakula S, Kamholz J, Grossman LI, Przyklenk K, Hüttemann, M (2018). Scientific Reports 8, 3481.
CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction. Purandare N, Somayajulu M, Hüttemann M, Grossman LI, Aras S. (2018). J Biol Chem, 293, 6517-6529.
Tissue-Specific Regulation of Cytochrome c by Posttranslational Modifications: Respiration, the Mitochondrial Membrane Potential, ROS, and Apoptosis. Kalpage HA, Bazylianska V, Recanati MR, Fite A, Liu J, Wan J, Mantena N, Malek MH, Podgorski I, Heath EI, Vaishnav A, Edwards B, Grossman LI, Sanderson TH, Lee I, and Hüttemann M (2018). FASEB J, 33: 1540-1553. PMID: 30222078
2017
Cytochrome c oxidase subunit 4 isoform 2 is essential for acute pulmonary oxygen sensing. Sommer N, Hüttemann M, Pak O, Scheibe S, Sinkler C, Malczyk M, Gierhardt M, Esfandiary A, Kraut S, Jonas F, Veith-Berger C, Aras S, Hecker M, Seeger W, Ghofrani HA, Schermuly RT, Grossman LI, Weissmann N (2017). Circulation Res 121:424-438.
Tissue- and Condition-specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: from Function to Human Disease.. Sinkler C, Kalpage H, Shay J, Lee I, Malek MH, Grossman LI and Huttemann M (2017). Oxidative Medicine and Cellular Longevity. Article ID 1534056, 19 pp. PMID: 28593021
MNRR1, a Biorganellar Regulator of Mitochondria.. Grossman LI, Purandare N, Arshad R, Gladyck S, Somayajulu M, Hüttemann M, and Aras S (2017). Oxidative Medicine and Cellular Longevity, Article ID 6739236, 12 pp. PMID: 28685009
Divergent lactate dehydrogenase isoenzyme profile in cellular compartments of primate forebrain structures.. Duka T, Collins Z, Anderson SM, Raghanti MA, Ely JJ, Hof PR, Wildman DE, Goodman M, Grossman LI, Sherwood CC (2017). Mol Cell Neurosci. 82:137-142. PMID: 28461219
Anti-mitochondrial antibodies to the enzyme components of the electron transport chain. The implications of mitochondrial autoimmunity in breast cancer.. Maroun M-C, Grossman LI, Lancaster W, Long M, Arshad R, Aboukasm G, Stark A, Burke M, Chitale D, Zarbo RJ, Peebles C, and Fernández Madrid F (2017). Open J Biotechnol Bioeng Diagn 1: 001-008.
Metformin, the aspirin of the 21st century: its role in gestational diabetes, prevention of preeclampsia and cancer, and the promotion of longevity.. Romero R, Erez O, Hüttemann M, Maymon E, Panaitescu B, Conde-Agudelo A, Pacora P, Yoon BH, Grossman LI (2017). Am J Obstet Gynecol 217:282-302.
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration. Aras S, Arrabi H, Punandare N, Hüttemann M, Kamholz J, Züchner S, Grossman LI. Biochim Biophys Acta, 1864: 440-448.
Phosphorylation of cytochrome c threonine 28 regulates electron transport chain activity in kidney. Mahapatra G, Varughese A, Ji Q, Lee I, Liu J, Vaishnav A, Sinkler C, Kapralov AA, Moraes CT, Sanderson TH, Stemmler TL, Grossman LI, Kagan VE, Brunzelle JS, Salomon AR, Edwards BFP, Hüttemann M. J Biol Chem 292: 64-79.
2016
COX7AR is a stress-inducible mitochondrial COX subunit that promotes breast cancer malignancy. Zhang K, Wang G, Zhang X, Hüttemann PP, Qiu Y, Liu J, Mitchell A, Lee I, Zhang C, Lee J, Pecina P, Wu G, Yang Z, Hüttemann Maik, Grossman LI. Sci Reports 6:31742. PMID: 27550821
High-throughput RNA sequencing reveals structural differences of orthologous brain-expressed genes between western lowland gorillas and humans. Lipovich L, Hou ZC, Jia H, Sinkler C, McGowen M, Sterner KN, Weckle A, Sugalski AB, Pipes L, Gatti D, Mason CE, Sherwood CC, Hof PR, Kuzawa CW, Grossman LI, Goodman M, Wildman DE. J Comp Neurol 524: 288-308. PMID: 26132897.
2015
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.Aras S,Bai M, Lee I, Springett R, Hüttemann M, Grossman LI (2015). Mitochondrion 20C, 43-51.
Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis. Fernández Madrid F, Maroun M-C, Olivero O, Long M, Stark A, Grossman LI, Binder W, Dong J, Burke M, Nathanson SD, Zarbo R, Chitale D, Zeballos-Chávez R, Peebles C. Cancer 15: 407. PMID: 25975273
Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines. Horsch M, Aguilar-Pimente JA, Bönisch C, Côme C, Kolster-Fog C, Jensen KT, Lund AH, Lee I, Grossman LI, Sinkler C, Hüttemann M, Bohn E, Fuchs H, Ollert M, Gailus-Durner V, Hrabê de Angelis M, Beckers J. PLoS One, 10(8):e0134503.
The brown and brite adipocyte marker Cox7a1 is not required for non-shivering thermogenesis in mice. Maurer SF, Fromme T, Grossman LI, Hüttemann M and Martin Klingenspor. Sci Reports 5: 17704.
2014
Developmental changes in the transcriptome of human cerebral cortex tissue: Long noncoding RNA transcripts
Lipovich L, Tarca A, Cai J, Jia H, Chugani HT, Sterner K, Grossman LI, Uddin M, Hof PR, Sherwood CC, Kuzawa CW, Goodman M, Wildman DE Cerebral Cortex 24: 1451-1459.
Characterization of human cortical gene expression in relation to glucose utilization.
Sterner KN, McGowen MR, Chugani HT, Tarca AL, Sherwood CC, Hof PR, Kuzawa CW, Boddy AM, Raaum RL, Weckle A, Liovich L, Grossman LI, Uddin M, Goodman M, Wildman DE (2013). Am J Hum Biol 25, 418-430. PMID: 23559490
Aerobic glycolysis in the primate brain: reconsidering the implications for growth and maintenance. Bauernfeind AL, Barksa SK, Duka T, Grossman LI, Hof PR, Sherwood CC (2014). Brain Structure and Function 219, 1149-1167. PMID: 24185460
Human testis specific genes are under relaxed negative selection.
Pierron D, Razafindrazaka H, Rocher C, Letellier T, Grossman LI (2014). Molec Genet Genomics 289, 37-45. PMID: 24202551
Regulation of cytochrome c in respiration, apoptosis, neurodegeneration and cancer – the good, the bad and the ugly.
Hüttemann M, Doan JW, Goustin AS, Sinkler C, Mahapatra G, Shay J, Liu J, Elbaz H, Aras S, Grossman LI, Ding Y, Zielske SP, Malek MH, Sanderson TH, Lee I (2014). In Cytochrome C: Electrochemistry, Biological Functions and Pathophysiological Implications. Hauppauge, NY: Nova Science Publishers. ISBN: 978-1-63117-467-4
Synaptosomal Lactate Dehydrogenase Isoenzyme Composition Is Shifted toward Aerobic Forms in Primate Brain Evolution.
Duka T, Anderson SM, Collins Z, Raghanti MA, Ely JJ, Hof PR, Wildman DE, Goodman M, Grossman LI, Sherwood CC (2014). Brain Behav Evol 83, 216-230.
Metabolic costs and evolutionary implications of human brain development.
Kuzawa CW, Chugani HT, Grossman LI, Lipovich L, Muzik O, Hof PR,Wildman DE, Sherwood CC, Leonard WR, Lange N (2014). Proc Natl Acad Sci USA 111, 13010-13015.
Reply to Skoyles: Decline in growth rate, not muscle mass, predicts the human childhood peak in brain metabolism.
Kuzawa CW, Chugani HT, Grossman LI, Lipovich L, Muzik O, Hof PR,Wildman DE, Sherwood CC, Leonard WR, Lange N (2014). Proc Natl Acad Sci USA 111, E4910.
2013
Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5, and CHCHD2
Aras S, Pak O, Sommer N, Finley RL Jr., Hüttemann M, Weissmann N, Grossman LI
Nucleic Acids Res 41: 2255-66. PMID: 23303788
Exposure to Ambient Particulate Matter Induces Non-alcoholic Steatohepatitis and Impairs Hepatic Glucose Metabolism in an Animal Model
Zheng Z, Xu X, Zhang X, Wang A, Zhang C, Hüttemann M, Grossman LI, Rajagopalan S, Chen LC, Sun Q, Zhang K
J Hepatology 58, 148-154.
Developmental changes in the transcriptome of human cerebral cortex tissue: Long noncoding RNA transcripts
Lipovich L, Tarca A, Cai J, Jia H, Chugani HT, Sterner K, Grossman LI, Uddin M, Hof PR, Sherwood CC, Kuzawa CW, Goodman M, Wildman DE
Cerebral Cortex, in press.
2012
Invited review: Regulation of mitochondrial respiration and apoptosis through cell signaling: Cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation
Hüttemann M, Helling S, Sanderson TH, Sinkler C, Samavati L, Mahapatra G, Varughese A, Lu G, Liu J, Ramzan R, Vogt S, Grossman LI, Doan JW, Marcus K, Lee I
Biochim Biophys Acta 1817: 598-609.
MITOGROUP: Continent-specific clusters of mitochondrial OXPHOS complexes based on nuclear non-synonymous polymorphisms
Pierron D, Letellier T and Grossman LI
Mitochondrion 12: 237-241.
Invited review: Cytochrome c oxidase: Evolution of control via nuclear subunit addition
Pierron D, Wildman DE, Hüttemann M, Markondapatnaikuni GC, Aras S and Grossman LI
Biochim Biophys Acta 1817: 590-597.
Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy
Hüttemann M, Klewer S, Lee I, Pecinova A, Pecina P, Liu J, Lee M, Doan JW, Larson D, Slack E, Maghsoodi B, Erickson RP, Grossman LI
Mitochondrion 12: 294-304.
Comparative analysis of encephalization in mammals reveals relaxed constraints on anthropoid primate and cetacean brain scaling
Boddy AM, McGowen MR, Sherwood CC, Grossman LI, Goodman M, Wildman DE
J Evol Biol 25: 981-94.
Dynamic Gene Expression in the Human Cerebral Cortex Distinguishes Children from Adults
Sterner KN, Weckle A, Chugani HT, Tarca AL, Sherwood CC, Hof PR, Kuzawa CW, Boddy AM, Abbas A, Raaum RL, Gregoire L, Lipovich L, Grossman LI, Uddin M, Goodman M and Wildman DE
PLoS One 7(5): e37714.
Cytochrome c oxidase subunit 4 isoform 2 knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology
Hüttemann M, Lee I, Gao X, Pecina P, Pecinova A, Liu J, Aras S, Sinkler C, Sommer N, Sanderson TH, Tost M, Neff F, Aguilar-Pimentel JA, Becker L, Naton B, Rathkolb B, Rozman J, Favor J, Hans W, Prehn C, Puk O, Schrewe A, Sun M, Höfler H, Adamski J, Bekeredjian R, Graw J, Adler T, Busch DH, Klingenspor M, Klopstock T, Ollert M, Wolf E, Fuchs H, Gailus-Durner V, Hrab de Angelis M, Weissmann N, Doan JW,. Bassett DJP, and Grossman LI
FASEB J 26, 3916-3930.
Dolphin genome provides evidence for adaptive evolution of nervous system genes and a molecular rate slowdown
McGowen MR, Grossman LI, and Wildman DE
Proc Royal Soc B 279, 3643-3651.
Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: respiration, apoptosis, and human disease
Hüttemann M, Lee I, Grossman LI, Doan JW, Sanderson TH
Adv Exp Med Biol 748: 237-64.
Evolution of the couple cytochrome c and cytochrome c oxidase in primates
Pierron D, Wildman DE, Hüttemann M, Letellier T, Grossman LI
Adv Exp Med Biol 748: 185-213.
Deletion of heart-type cytochrome c oxidase subunit 7A1 impairs skeletal muscle angiogenesis and oxidative phosphorylation
Lee I, Hüttemann M, Liu J, Grossman LI, Malek MH
J Physiol 590, 5231-5243.
Current relaxation of selection on the human genome: Tolerance of deleterious mutations on olfactory receptors
Pierron D, Cortés NG, Letellier T, Grossman LI
Mol Phylogenet Evol, in press.
2011
Silencing, positive selection and parallel evolution: Busy history of primate cytochromes c
Pierron D, Opazo JC, Heiske M, Papper Z, Uddin M, Chand G, Wildman DE, Romero R, Goodman M, Grossman LI
PLOS One, 6(10): e26269.
2009
A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death
Than NG, Romero R, Goodman M, Weckle A, Xing J, Dong Z, Xu Y, Tarquini F, Szilagyi A, Gal P, Hou Z, Tarca AL, Kim CJ, Kim JS, Haidarian S, Uddin M, Bohn H, Benirschke K, Santolaya-Forgas J, Grossman LI, Erez O, Hassan SS, Zavodszky P, Papp Z and Wildman DE
Proc Natl Acad Sci USA 106: 9731-9736.
Phylogenomic Analyses Reveal Convergent Patterns of Adaptive Evolution in Elephant and Human Ancestries
Goodman M, Sterner KN, Islam M, Uddin M, Sherwood CC, Hof PR, Hou ZC, Lipovich L, Jia H, Grossman LI and Wildman DE
Proc Natl Acad Sci USA 106: 20824-29.
2008
Molecular evolution of the cytochrome c oxidase subunit 5A gene in primates
Uddin M, Opazo JC, Wildman DE, Sherwood CC, Hof P, Goodman M and Grossman LI
BMC Evol Biol 8:8.
Mammalian progesterone receptors show evidence of adaptive evolution associated with N-terminus transactivation and transrepression function
Chen C, Opazo JC, Erez O, Uddin M, Santolaya-Forgas J, Goodman M, Grossman LI, Romero R and Wildman DE
Mol Phylogenet Evol 47, 637-649.
Distinct genomic signatures of adaptation in pre-and post-natal environments during human evolution
Uddin M, Goodman M, Erez O, Romero R, Liu G, Islam M, Opazo JC, Sherwood CC, Grossman LI and Wildman DE
Proc Natl Acad Sci USA 105, 3215-3220.
Emergence of hormonal and redox regulation of galectin-1 in placental mammals – implication in maternal-fetal immune tolerance
Than NG, Romero R, Erez O, Weckle A, Hotra J, Abbas A, Han YM, Kim S-S, Kusanovic JP, Gotsch F, Hou Z, Santolaya-Forgas J, Benirschke K, Papp Z, Grossman LI, Goodman M and Wildman DE
Proc Natl Acad Sci USA 105: 15819-24.
2007
OCPAT: an online codon-preserved alignment tool for evolutionary genomic analysis of protein coding sequences
Liu G, Uddin M, Goodman M, Grossman LI, Romero R and Wildman DE.
Source Code for Biology and Medicine 2:5.
Genomics, biogeography, and the diversification of placental mammals
Wildman DE, Uddin M, Opazo JC, Liu G, Lefort V, Gascuel O, Grossman LI, Romero R and
Goodman M.
Proc Natl Acad Sci USA 104, 14395-14400.
2006
Evolution of the mammalian placenta revealed by phylogenetic analysis
Wildman DE, Chen C, Erez O, Grossman LI, Goodman M and Romero R.
Proc Natl Acad Sci USA 103, 3203-3208.
New Prospects for an Old Enzyme: Mammalian Cytochrome c is Tyrosine Phosphorylated in vivo
Lee I, Salomon AR, Yu K, Doan JW, Grossman LI and Hüttemann M.
Biochemistry 45, 9121-9128.
Evolution of Increased Glia-Neuron Ratios in the Human Frontal Cortex
Sherwood CC, Stimpson CD, Raghanti MA, Wildman DE, Uddin M, Grossman LI, Goodman M, Redmond JC, Bonar CJ, Erwin JM and Hof PR.
Proc Natl Acad Sci USA, 103, 13606-13.
2005
Rapid electrostatic evolution at the docking site for cytochrome c on cytochrome c oxidase in anthropoid primates
Schmidt TR, Wildman DE, Uddin M, Opazo J, Goodman M and Grossman LI.
Proc Natl Acad Sci USA 102, 6379-6384.
Rapid nonsynonymous evolution of the iron sulfur protein in anthropoid primates
Doan JR, Schmidt TR, Wildman DE, Goodman M, Weiss ML and Grossman LI.
J Bioenerg Biomembr 37, 35-41.
Transcription of cytochrome c oxidase subunit IV-2 is controlled by a novel conserved oxygen responsive element
Hüttemann M, Lee I, Liu J and Grossman LI.
FEBS J 274, 5737-5748.
cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity
Lee I, Salomon AR, Ficarro S, Mathes I, Lottspeich F, Grossman LI, and Hüttemann M (2005).
J Biol Chem 280, 6094-6100.
Moving primate genomics beyond the chimpanzee genome
Goodman M, Grossman LI and Wildman DE.
Trends Genet 21, 511-517.
2004
Sister-grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles
Uddin M, Wildman DE, Liu G, Xu W, Johnson RM, Hof P, Kapatos G, Grossman LI, and Goodman M.
Proc Natl Acad Sci USA 101, 2957-2962.
Coevolution of a multiprotein complex: cytochrome c oxidase subunits show accelerated rates of nonsynonymous substitution in anthropoid primates
Doan JR, Schmidt TR, Wildman DE, Uddin M., Goldberg A, Hüttemann M, Goodman M, Weiss ML, and Grossman LI.
Mol Phylogenet Evol 33, 944-950.
Accelerated evolution of the electron transport chain in anthropoid primates
Grossman LI, Wildman DE, Schmidt TR and Goodman M.
Trends Genet 20, 579-585.
2003
Retention of a duplicate gene through changes of the subcellular localization signal: a cytochrome c oxidase subunit VIIa-related protein localizes to the Golgi apparatus
Schmidt TR, Doan JR, Goodman M and Grossman LI.
J Mol Evol 57, 222-228.
Adaptive evolution of cytochrome c oxidase subunit viii in anthropoid primates
Goldberg A, Schmidt TR, Hüttemann M, Wildman DE, Weiss M, Goodman M and Grossman LI.
Proc Natl Acad Sci USA 100, 5873-5878.
Cytochrome c oxidase of mammals contains a testes-specific isoform of subunit VIb—the counterpart to testes-specific cytochrome c?
Hüttemann M, Jaradat S and Grossman LI.
Molec Repro Dev 66, 8-16.
A third isoform of cytochrome c oxidase subunit VIII is present in mammals
Hüttemann M, Schmidt TR and Grossman LI.
Gene 312, 95-102.
Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: Enlarging genus Homo
Wildman DE, Uddin M, Liu G, Grossman LI and Goodman M.
Proc Natl Acad Sci USA 100, 7181-7188.
2002
Amino acid replacement is rapid in primates for the mature polypeptides of COX subunits, but not for their targeting presequences
Schmidt TR, Goodman M and Grossman LI.
Gene 286, 13-19.
Genomic organization and promoter regulation of human cytochrome c oxidase subunit VIIa heart/muscle isoform (COX7AH)
Yu M, Jaradat SA and Grossman LI.
Biochim Biophys Acta 1574, 345-353.
Human and chimpanzee functional DNA shows they are more similar to each other than either is to other apes
Wildman DE, Grossman LI, and Goodman M.
In M Goodman and A.S. Moffat, Eds., Probing Human Origins. Cambridge: American Academy of Arts & Sciences Press, pp. 1-10.
Episodic positive selection in ape cytochrome c oxidase subunit IV
Wildman DE, Wu W, Goodman M and Grossman LI.
Mol Biol Evol 19, 1812-1815
2001
The evolution of nuclear and mitochondrial encoded subunit interaction in cytochrome c oxidase
Schmidt TR, Wu W, Goodman M and Grossman LI.
Mol.Biol Evol 18, 563-569.
Molecular evolution of aerobic energy metabolsim in primates
Grossman LI, Schmidt TR, Wildman D and Goodman M.
Mol Phylogenet Evol 18, 26-36.
Mammalian subunit IV isoforms of cytochrome c oxidase
Hüttemann M, Kadenbach B and Grossman LI.
Gene 267, 111-123.
2000
Isolation and sequence of the human cytochrome c oxidase subunit VIIaL gene
Hüttemann M, Mühlenbein N, Schmidt TR, Grossman LI and Kadenbach B.
Biochim Biophys Acta 1492, 252-258.
Molecular evolution of cytochrome c oxidase subunit I in primates: Is there co-evolution between mitochondrial and nuclear genomes?
Wu W, Schmidt TR, Goodman M and Grossman LI.
Mol Phylogenet Evol 17, 294-304.
Global brain ischemia and reperfusion: Molecular mechanisms of neuronal injury
White BC, Sullivan JM, DeGracia DJ, O'Neill BJ, Newmar RW, Grossman LI, Rafols JA and Krause GS.
J Neurol Sci 179, 1-33.
A primate genome project deserves high priority
McConkey EH and Varki A. Cosignatories: Allman J, Benirschke K, Crick F, Deacon TW, de Waal F, Dugaiczyk A, Gagneux P, Goodman M, Grossman LI, Gumucio D, Insel T, Kidd KK, King M-C, Krauter K, Kucherlapati R, Motulsky AG, Nelson D, Oefner P, Palade G, Ruvolo M, Ryder OA, Sikela J, Stewart C-B, Stone A & Woodruff D.
Science 289, 1295-6.
1999
COX4, the gene for cytochrome c oxidase subunit IV, and NOC4, a closely linked gene, are controlled by a bidirectional promoter
Bachman NJ, Wu W, Schmidt TR, Grossman LI and Lomax MI.
Mamm Genome 10, 506-512.
Molecular evolution of the COX7A gene family in primates
Schmidt TR, Goodman M and Grossman LI
Mol Biol Evol 16, 619-626.
1998
Transcriptional regulation of mammalian cytochrome c oxidase genes
Grossman LI, Seelan RS and Jaradat SA.
Electrophoresis 19, 1254-1259.
Tissue specific expression and mapping of the Cox7ah gene in mouse
Jaradat SA, Ko, MSH and Grossman LI.
Genomics 49, 363-370.
1997
Molecular evolution of cytochrome c oxidase subunit IV: evidence for positive selection in simian primates
Wu W, Goodman M, Lomax MI and Grossman LI.
J Mol Evol 44, 477-491.
Invited review: Nuclear genes for cytochrome c oxidase
Grossman LI and Lomax MI.
Biochim Biophys Acta 1352, 174-192.
Structural organization and promoter analysis of the bovine cytochrome c oxidase subunit VIIc gene: A functional role for YY1
Seelan RS and Grossman LI.
J Biol Chem 272, 10175-10181.
Molecular evolution of mammalian cytochrome c oxidase: rate variation between subunit VIa isoforms
Schmidt T, Jaradat SA, Goodman M, Lomax MI and Grossman LI.
Mol Biol Evol 14, 595-601.
Prior to 1997
The reaction of α-bromoketones with triphenylphosphine — a novel debromination
Borowitz IJ and Grossman LI (1962).
Tetrahedron Letters 11, 471-474.
Starch-gel electrophoresis of malate dehydrogenase
Thorne CJR, Grossman LI and Kaplan NO (1963).
Biochim Biophys Acta 73, 193-203.
Photodynamic degradation of nucleic acids
Bellin JS and Grossman LI (1965).
Photochem Photobiol 4, 45-53.
Mitochondrial DNA in yeast and some mammalian species
Corneo G, Moore C, Sanadi DR, Grossman LI and Marmur J (1966).
Science 151, 687-689.
Physical studies on the structure of yeast mitochondrial DNA
Shapiro L, Grossman LI, Marmur J and Kleinschmidt AK (1968).
J Mol Biol 33, 907-922.
Preferential synthesis of yeast mitochondrial DNA in the absence of protein synthesis
Grossman LI, Goldring ES and Marmur J (1969).
J Mol Biol 46, 367-376.
The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromide
Goldring ES, Grossman LI, Krupnick D, Cryer DR and Marmur J (1970).
J Mol Biol 52, 323-335.
The petite mutation in yeast. II. Isolation of mutants containing mitochondrial DNA of reduced size
Goldring ES, Grossman LI and Marmur J (1971).
J Bacteriol 107, 377-381.
The petite mutation in yeast. III. Nearest neighbor analysis of normal and mutant mitochondrial DNA
Grossman LI, Cryer DR, Goldring ES and Marmur J (1971).
J Mol Biol 62, 565-575.
The presence of ribonucleotides in mature closed circular mitochondrial DNA
Grossman LI, Watson R and Vinograd J (1973).
Proc Natl Acad Sci USA 70, 3339-3343.
Replication and structure of animal mitochondrial DNA
Kasamatsu H, Grossman LI, Robberson D, Watson R and Vinograd J (1973).
Cold Spring Harbor Symp Quant Biol 38, 281-288.
Restricted uptake of ethidium bromide and propidium diiodide by denatured closed circular DNA in buoyant CsCl
Grossman LI, Watson R and Vinograd J (1974).
J Mol Biol 86, 271-283.
Isolation of superhelix relaxation protein from nuclei of cultured mouse and human cells and partial characterization
Vosberg HP, Grossman LI and Vinograd J (1975).
Eur J Biochem 55, 79-93.
A simple and rapid coordinate measurement system for large molecule oscillation photographs
Grossman LI and Petsko GA (1976).
J Appl Cryst 9, 416-417.
Detection of a contaminant cell culture line by restriction endonuclease cleavage patterns of mitochondrial DNA
Grossman LI, Parker RC, Watson R, Chandler SEW and Teplitz M (1977).
Nucleic Acids Res 4, 1267-1271.
A restriction endonuclease cleavage map of mouse mitochondrial DNA
Moore KH, Johnson PH, Chandler SEW and Grossman LI (1977).
Nucleic Acids Res 4, 1273-1289.
Electrophoresis of DNA in agarose gels. Optimizing separations of conformational isomers of duplex and single-stranded DNA
Johnson PH and Grossman LI (1977).
Biochemistry 16, 4217-4225.
Jerome Vinograd Memorial Issue
Davidson N, Bauer W, Felsenfeld G, Grossman LI and Soll D, editors (1977).
Nucleic Acids Res 4, number 5.
Enhancement of buoyant separations between DNAs in preparative CsCl gradients containing distamycin A or netropsin
Tatti KM, Hudspeth ME, Johnson PH and Grossman LI (1978).
Analyt Biochem 88, 561-571.
Isotope overlap corrections
Grossman LI (1978).
Hewlett-Packard Users Library Solutions in Physics, pp. 43-46. [Computer program].
Electrophoretic characterization of intracellular forms of bacteriophage phi-X174 DNA. The identification of novel intermediates of altered superhelix density
Johnson PH, Wild E, Miller MJ and Grossman LI (1979).
J Virol 32, 629-639.
Electrophoresis of DNA in agarose gels. II. Factors affecting errors in the measurement of electrophoretic mobilities
Johnson PH, Miller MJ and Grossman LI (1980).
Analyt Biochem 102, 159-162.
Rapid purification of yeast mitochondrial DNA in high yield
Hudspeth ME, Shumard DS, Tatti KM and Grossman LI (1980).
Biochim Biophys Acta 610, 221-228.
The var1 determinant region on yeast mitochondrial DNA
Butow RA, Farrelly F, Zassenhaus HP, Hudspeth MES, Grossman LI and Perlman PS (1982).
In Mitochondrial Genes (eds. G Attardi, P Borst and PP Slonimski), Cold Spring Harbor Laboratory, pp. 241-253.
Location and structure of the var1 gene on yeast mitochondrial DNA: Nucleotide sequence of the 40.0 allele
Hudspeth MES, Ainley WM, Shumard DS, Butow RA and Grossman LI (1982).
Cell 30, 617-626.
Recombinant DNA and basic research: What we have learned
Grossman LI and Moore GP (1983).
LSA Magazine 6, 15-20.
Organization of Achlya mitochondrial DNA: A population with two orientations and a large inverted repeat containing the ribosomal RNA genes
Hudspeth MES, Shumard DS, Bradford CJR and Grossman LI (1983).
Proc Natl Acad Sci USA 80, 142-146.
The unusual organization of the yeast mitochondrial var1 gene
Butow RA, Ainley WM, Zassenhaus HP, Hudspeth ME and Grossman LI (1983).
In Manipulation and Expression of Genes in Eukaryotes (eds. P. Nagley, A.W. Linnane, A.W. Peacock and J.A. Pateman), Academic Press, Sydney, pp. 269-277.
Transcriptional mapping of the yeast mitochondrial var1 gene: Anomalous hybridization of RNA from AT-rich regions
Zassenhaus HP, Farrelly F, Hudspeth MES, Grossman LI and Butow RA (1983).
Molec Cell Biol 3, 1615-1624.
The expandable var1 gene of yeast mitochondrial DNA: In-frame insertions can explain the strain-specific protein size polymorphisms
Hudspeth MES, Vincent RD, Perlman PS, Treisman LO, Shumard DS and Grossman LI (1984).
Proc Natl Acad Sci USA 81, 3148-3152.
The frequency of matching sequences in DNA
Moore GP, Moore AR and Grossman LI (1984).
J Theoret Biol 108, 111-122.
Isolation and characterization of a cDNA clone for bovine cytochrome c oxidase subunit IV
Lomax MI, Bachman NJ, Nasoff M, Caruthers MH and Grossman LI (1984).
Proc Natl Acad Sci USA 81, 6295-6299.
Fungal Mitochondrial Genomes
Grossman LI and Hudspeth ME (1985).
In Gene Manipulations in Fungi (eds. JW Bennett and LL Lasure), Academic Press, pp. 66-103.
The unusual var1 gene of yeast mitochondrial DNA
Butow RA, Perlman PS and Grossman LI (1985).
Science 228, 1496-1501.
SPLINT: A cubic spline interpolation program for the analysis of fragment sizes in one-dimensional electrophoresis gels
Gariepy CE, Lomax MI and Grossman LI (1986).
Nucleic Acids Res 14, 575-581.
Analysis of the mitochondrial and nuclear genomes of two basidiomycetes, Coprinus cinereus and Coprinus stercorarius
Cooper CA, Hudspeth MES, Moore GP and Grossman LI (1986).
Current Genet 10, 515-525.
Achlya mitochondrial DNA: gene localization and analysis of inverted repeats
Shumard DS, Grossman LI and Hudspeth MES (1986).
Molec Gen Genet 202, 16-23.
Two bovine genes for cytochrome c oxidase subunit IV: a processed pseudogene and an expressed gene
Bachman NJ, Lomax MI and Grossman LI (1987).
Gene 55, 219-229.
Isolation of a cDNA clone encoding subunit IV of human cytochrome c oxidase
Zeviani A, Miranda AF, Herbert J, Lomax MI, Grossman LI, Sherbany AA, DiMauro S and Schon EA (1987).
Gene 55, 205-217.
Mitochondrial DNAs of Suillus: Threefold size change in molecules that share a common gene order
Bruns TD, Palmer JD, Shumard DS, Grossman LI and Hudspeth MES (1988).
Current Genet 13, 49-56.
Brain DNA during cardiac arrest and reperfusion: initial studies
White BC, Grossman LI, Krause GS, Todd IK and O'Neill BJ (1988).
Ann Emerg Med 17, 162-163.
Nucleotide sequence of a cDNA for bovine cytochrome c oxidase subunit VIIa
Seelan RS, Scheuner D, Lomax MI and Grossman LI (1989).
Nucleic Acids Res 17, 6410.
Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase
Fabrizi GM, Rizzuto R, Nakase H, Mita S, Lomax MI, Grossman LI and Schon EA (1989).
Nucleic Acids Res 17, 7107.
Nucleotide sequence of a cDNA for bovine cytochrome c oxidase subunit VIIc
Aqua MS, Lomax MI, Schon EA and Grossman LI (1989).
Nucleic Acids Res 17, 8376.
Tissue-specific genes for respiratory proteins
Lomax MI and Grossman LI (1989).
Trends Biochem Sci 14, 501-503.
Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV
Lomax MI, Welch MD, Darras BT, Francke U and Grossman LI (1990).
Gene 86, 209-216.
Invited editorial: mitochondrial DNA in sickness and in health
Grossman LI (1990).
Am J Hum Genet 46, 415-417.
Sequence of a cDNA specifying subunit VIIc of human cytochrome c oxidase
Koga Y, Fabrizi GM, Mita S, Arnaudo E, Lomax MI, Aqua MS, Grossman LI and Schon EA (1990).
Nucleic Acids Res 18, 684.
Sequence of a cDNA specifying subunit VIIc of mouse cytochrome c oxidase
Akamatsu M and Grossman LI (1990).
Nucleic Acids Res 18, 3645.
Sequence of a mouse cDNA for subunit IV of cytochrome c oxidase
Grossman LI and Akamatsu M (1990).
Nucleic Acids Res 18, 6454.
Nucleotide sequence of a cDNA encoding encoding subunit VIIa of rat liver cytochrome c oxidase
Enders C, Schlerf A, Mell O, Grossman LI and Kadenbach B (1990).
Nucleic Acids Res 18, 7143.
Gel electrophoresis of DNA53. Grossman LI (1991).
In Proceedings of the International Symposium on the Forensic Aspects of DNA Analysis, U.S. Government Printing Office, pp. 37-46.
Brain nuclear DNA survives cardiac arrest and reperfusion
White BC, DeGracia DJ, Krause GS, Skjaerlund J, O'Neill BJ and Grossman LI (1991).
Free Rad Biol Med 10, 125-135.
A rapid protocol to isolate DNA fragments from low melting temperature agarose
Seelan RS and Grossman LI (1991).
BioTechniques 10, 186-188.
Characterization and expression of a cDNA for subunit VIIc of bovine cytochrome c oxidase
Aqua MS, Bachman NJ, Lomax MI and Grossman LI (1991).
Gene 104, 211-217.
The cDNA for the heart/muscle isoform of bovine cytochrome c oxidase subunit VIa encodes a presequence
Smith EO, Bement DM, Grossman LI and Lomax MI (1991).
Biochim Biophys Acta 1089, 266-268.
Cytochrome c oxidase subunit VIIa isoforms: characterization and expression of bovine cDNAs
Seelan RS and Grossman LI (1991).
J Biol Chem 266, 19752-19757.
Brain mitochondrial DNA is not damaged by prolonged cardiac arrest or reperfusion
White BC, Tribhuwan RC, Vander Laan DJ, DeGracia DJ, Krause GS and Grossman LI (1992).
J Neurochem 58, 1716-1722.
Rapid evolution of the human gene for cytochrome c oxidase subunit IV
Lomax MI, Hewett-Emmett D, Yang T and Grossman LI (1992).
Proc Natl Acad Sci USA 89, 5266-5270.
Structure and organization of the heart isoform gene for bovine cytochrome c oxidase subunit VIIa
Seelan RS and Grossman LI (1992).
Biochemistry 31, 4696-4704.
Tissue-specific expression and chromosome assignment of mRNAs specifying two isoforms of subunit VIIa of human cytochrome c oxidase
Arnaudo E, Hirano M, Seelan RS, Milatovich A, Hsieh C-L, Fabrizi GM, Grossman LI, Francke U and Schon EA (1992).
Gene 119, 299-305.
Studies of the protein synthesis system in the brain cortex after a 20-minute cardiac arrest and during reperfusion
DeGracia DJ, O'Neill BJ, Frisch C, Krause GS, Skjaerlund JM, White BC, and Grossman LI (1993).
Resuscitation 25, 161-170.
Potential role of growth factors in global brain ischemia and reperfusion: Observation of insulin-driven tyrosine phosphorylation of a 90-kDa protein during reperfusion
White BC, Krause GS, O'Neill BJ, DeGracia DJ, Tiffany BR, Grossman LI and Grunberger G (1993).
Ann NY Acad Sci 692, 281-283.
Membrane damage and repair in brain injury by ischemia and reperfusion
White BC, Krause GS and Grossman LI (1993).
Neurology 43, 1656-1665.
Insulin induces tyrosine phosphorylation of a 90-kDa protein during post-ischemic brain reperfusion
DeGracia DJ, O'Neill BJ, White BC, Tiffany BR, Krause GS, Grossman LI and Grunberger G (1993).
Exp Neurology 124, 351-356.
Structural organization and evolution of the liver isoform gene for bovine cytochrome c oxidase subunit VIIa
Seelan RS and Grossman LI (1993).
Genomics 18, 527-536.
Antisense inhibition of nuclear-encoded cytochrome c oxidase subunits IV and VIIc activity in the pre-implantation embryo
Ao A, Erickson RP, Rosenthal NH and Grossman LI (1993).
Dev Genet 14, 393-396.
Global brain ischemia and reperfusion by cardiac arrest and resuscitation: Mechanisms leading to death of vulnerable neurons and a fundamental basis for therapeutic approaches
O'Neill BJ, Krause GS, Grossman LI, Grunberger G, Rafols JA, DeGracia DJ, Newmar RW, Tiffany BR and White BC (1995).
In Cardiac arrest: the science and practice of resuscitation medicine (ed. NA Paradis, HR Halperin, RM Nowack), pp. 84-112, Williams and Wilkins, Baltimore, MD.
Cloning, sequence analysis, and expression of a mouse cDNA encoding cytochrome c oxidase subunit VIa liver isoform
Grossman LI, Rosenthal N, Akamatsu M and Erickson RP (1995).
Biochim Biophys Acta 1260, 361-364.
Invited article: Mitochondrial mutations and human disease
Grossman LI (1995).
Environ Mol Mutagen 25 (Suppl. 26), 30-37.
Invited article: Global brain ischemia and reperfusion
White BC, Grossman LI, O'Neill BJ, DeGracia DJ, Newmar RW, Rafols JA and Krause GS (1996).
Ann Emerg Med 27, 588-594.
Cytochrome c oxidase subunit VIIa liver isoform: Characterization and identification of promoter elements in the bovine gene
Seelan RS, Gopalakrishnan L, Scarpulla RC and Grossman LI (1996).
J Biol Chem 271, 2112-2120.
Invited article: Human mitochondrial genetics and disease
Grossman LI and Shoubridge EA (1996).
BioEssays 18, 983-991.